Primer

Considerations when Selecting a Matrix for MALDI

Aug 31, 2021

One of the most widely utilized techniques in mass spectrometry imaging (MSI) is label-free MALDI (Matrix-Assisted Laser Desorption Ionization), which can be coupled to a variety of mass analyzers to create brilliant molecular maps. Application targets include lipids, proteins, peptides, drugs, and ... More

Primer

Is Your Flow Cytometer Reliable?

Aug 31, 2021

Flow cytometry provides a useful method by which scientists can measure and analyse different properties of individual cells, including size, internal complexity (granularity) and the presence of cell surface and intracellular markers using fluorescence. Flow can help identify individual cell subpop... More

Primer

Unwanted Fungi: Detecting Microbial Cell Culture Contamination

• Translational Medicine
• Analytical Testing
• Drug Discovery

Aug 31, 2021

Coming into the lab and spotting an obvious fungal growth, or the tell-tale signs of cloudy media, can be a stressful experience for researchers. When carrying out cell culture in the lab, contamination from microbial agents such as bacteria and fungus can occur and have disastrous effects on ongoin... More

Primer

Source and Elimination of Common Mass Spectrometry Contaminants

• OMICS
• Translational Medicine

Aug 31, 2021

Sensitivity is a key attribute of mass spectrometers to allow quantification of minute amounts of analytes. Yet this sensitivity can be a conundrum. Myriad sources can contribute contaminants that can impact background and confound interpretation of results. An increased background signal can make i... More