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GEN Protocols

Computational Biosciences

Computational Biosciences

Application

Benchling for Gene Therapy & Gene Editing R&D

Modern gene therapy requires investigation of a wide variety of genes of interest, engineering of delivery vectors, and optimization of vector production processes. This necessitates a strong digital foundation to comprehensively characterize gene therapy candidates to bring the best products into t... More


Application

The Benchling Life Sciences R&D Cloud

Life science R&D is becoming more complex. Companies need software built for the new way of doing science, or they risk falling behind the next generation of therapeutic development. Enter Benchling. Benchling connects the entire R&D lifecycle — from project documentation and data acquisition to seq... More


Protocol

Detergent-Free Nuclei Isolation

A novel spin column-based approach to isolate intact single nuclei from tissues (fresh or frozen) and cells without using a detergent. The protocol is fast, easy, and reliable, producing high-quality single nuclei with minimized clumping and possible leakage of the nuclear envelope. The protocol is ... More


Application

Benchling for RNA Therapeutics R&D

Because RNA therapeutics can target conditions that small molecules and proteins cannot address, researchers are now on the verge of treating previously “undruggable” diseases. From the approval of the first antisense oligonucleotide, aptamer, and siRNA, to the now famous launch of mRNA-based COVID-... More


Application

Benchling for Cell Therapy R&D

Cell therapies such as stem cells, CAR T cells, and TCR have been of significant interest in research over the past few decades. The FDA approval of CAR T therapies has led to renewed interest in the field. As companies rush to bring more novel cell therapies to the market, they face several R&D com... More


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