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GEN Protocols

Cancer Research

Protocol

CodePlex Secretome

This protocol outlines the standard method for thawing and loading samples onto the CodePlex chip. ... More


Protocol

Noninvasive 3D imaging Using Optical Coherence Tomography

This protocol describes a novel OCT-based technology for imaging and analysis of 3D structures, such as, spheroid /organoids, tissues for growth morphological evaluation, quantification of internal cavities, drug sensitivity testing to capture the events leading to tumor cell death, and assessing e... More


Protocol

Streamlined High Throughput Drug Screening with PrimeSurface® White 384 well 3D plates

Using PrimeSurface® white plate, cancer spheroid cells can be formed and tested for drug screening using luminescence viability assay in the same well without the need for reagent transfer. This streamlined process shortens the experimental steps and time required in drug testing thus providing a ro... More


Protocol

Evaluate Cell Therapy Product Purity with Aura CL

The CAR-T development workflow is a multi-step process that includes transfection of T cells with a viral vector to express a chimeric antigen and activation/expansion of the CAR-T using a molecule like a Dynabead conjugated to CD3/CD28. Each of these steps is a potential source of contamination tha... More


Protocol

Detect Specific Protein Aggregates in Biologic Formulations with the Aura Immunoassay

Biologic co-formulations target multiple pharmacologically active sites to increase therapy efficacy. However, either biologic can be a source of protein aggregation that can negatively influence the product’s safety, efficacy, and therapy. Aura systems are the only particle analyzer that can pinpoi... More


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