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Batch-to-batch consistency of premium grade bioactive proteins

Abcam

Jan 28, 2022

Abstract

​​​​This white paper demonstrates the batch-to-batch consistency of our premium grade bioactive proteins (growth factors and cytokines). Designed to meet the exacting demands of cell and gene therapy applications, our premium grade proteins are ideal for controlled cell culture. ​​​​​​​​​​​​​​​​​​​​​​​​​​​From basic to translational research and clinical applications, cell culture is an essential technique that underpins the generation of promising cell and gene therapies. Since the quality of cytokines and growth factors can significantly influence the properties and function of cultured cells, these bioactive proteins must be produced to the highest standards to ensure the same reproducible results over a 5-15 years development timeline. This will enable cell and gene therapies to transition smoothly from early discovery to clinical development. To help you meet the ongoing cell and gene therapy production demands today and in the future, Abcam has launched a range of recombinantly produced premium grade cytokines and growth factors with class-leading consistency. The consistent performance of Abcam’s premium grade bioactive proteins enables a smooth transition from research to clinical development, saving your time and resources. Their batch-to-batch consistency also allows these proteins to fulfill additional applications efficiently across a wide range of cell culture discovery and basic research techniques, including in vivo and in vitro assay development, compound screening, and structural studies. This white paper demonstrates: Our manufacturing workflow for producing premium grade recombinant human cytokines and growth factors - How we access the purity and batch-to-batch consistency of our premium range bioactive proteins - Biophysical QC and bioactive assay batch data for the production of three premium grade bioactive proteins: two recombinant human cytokines, TNF-α and IL-3, and one recombinant human growth factor EGF


Application File

premium-bioactive-protein-white-paper_(compressed).pdf

Comments

Edward Palombo Feb 26, 2022

Interesting concept, would it be beneficial to understand where the proteins originated from that your immune cells use to recognize a individuals cells from foreign cells ?

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